4 PROVEN Ways to Get Rid of COLD SORES for Good

So you have a cold sore. What does that mean? How do you make it go away? More importantly, how can you make them stay away? Let’s find out. (OR you can skip the read and scroll down to the end of this article for the TAKE ACTION points.)

Cold sores (also known as fever blisters) are unsightly blisters that form on or around the mouth due to a viral infection: the herpes simplex virus (HSV-1). Yes, this is similar to the herpes simplex virus (HSV-2) which causes genital herpes. It is extremely contagious, which is why 50 to 80 percent of Americans have oral herpes. If a person with oral herpes performs oral sex, it can result in genital herpes for the receiver. If a person without herpes gives someone with genital herpes oral sex, it can result in oral herpes for the giver. Oral herpes can be spread very easily through shared drinks, kissing, and by coming in contact with anything that was also in contact with a herpes blister. This virus can infect men, women, children, and elderly alike. It is more common than most people realize, so if you suffer from cold sores, you are certainly not alone.

There are many topical treatments available for cold sores once they have already presented. Some of these treatments focus on alleviating symptoms (burning, itching, tingling, oozing, crusting blisters), and some of them focus on reduction of healing time and preventing replication of the virus. There are also oral antivirals available by prescription, but unless your case is very severe, these probably aren’t necessary.

The Most POWERFUL topical treatment: OZONE

Ozone therapy has many useful applications. Lucky for you, killing the herpes virus and improving immune system action is one of them! A study conducted by Aravinda et al (2016) demonstrated a 100% resolution of herpes blisters with twice per day topical application of ozonated oil in only 2.2 days with no adverse reactions. (Typically, herpes blisters can last for up to two weeks.) Another study by Gao et al (2018) demonstrated that twice per day “topical ozone therapy in patients with herpes zoster is helpful in relieving pain, shortening the course as well as improving the clinical efficacy without obvious adverse reactions.” So, if you start to feel a tingle on your lip, put ozone oil on the spot immediately. If the sore has already erupted, make sure to apply ozone oil twice per day.  Although the study I mentioned uses ozone olive oil, the most powerful ozonated oils are PurO3 Ozonated Hemp Oil or PurO3 Ozonated Jojoba Oil

Now onto PREVENTION and CONTROL

Unfortunately, there is no cure. The virus lies dormant in nerves and waits until the immune system is down (for example, if a person gets sick, is more stressed out than usual, or hasn’t been sleeping well), and then it becomes activated and the blisters present.

So how can you prevent them from recurring so that you don’t have to feel ashamed of your face anymore?

L-Lysine

The amino acid L-Lysine has long been known to keep viral conditions such has herpes simplex under control (Chaitow, 1985). In the intestine, lysine competes with arginine being absorbed in the intestine, which works to limit the energy source the virus needs to replicate. It is also assumed that there are some other unknown mechanisms in which it inhibits viruses, and lysine is frequently given to people with other types of chronic viral infections.

Patients who showed improvement in the studies I have encountered were taking dosages of 300 mg to 1200 mg daily. A study conducted by Behforooz et al (1987) demonstrated significant improvement and reduction of recurrence with 1000 mg 3 times per day for six months.

Monolaurin and Lauric Acid

Monolaurin and lauric acid have powerful antiviral, antibacterial, and antifungal properties. They are found in human breast milk, and (far more conveniently) in organic, virgin, unrefined coconut oil. Coconut oil has many other benefits as well. The Coconut Oil Miracle is an interesting read and will expose you to the history of coconut oil its multitude of health benefits.

If you can’t stand the taste of coconut oil, you can also find monolaurin in a pill form which is marketed as Lauricidin. One dose of Lauricidin is the equivalent of taking many tablespoons of coconut oil, and the typical dosage for herpes is about 1/2 to 1 scoop, one to three times per day (Weston A. Price Foundation, 2019).

So, if you are tired of trying to cover your cold sore, and you don’t want to answer the question “what’s that on your lip?” anymore, give one or all of these a try to keep the outbreaks under control.


TAKE ACTION points:

1. Topical ozone oil for active lesions: Rinse area with water and apply at least twice per day. Although the study I mentioned uses ozone olive oil, the most powerful ozonated oils are made with PurO3 Ozonated Hemp Oil
or PurO3 Ozonated Jojoba Oil

2. L-Lysine: 500 mg to 1000 mg three times per day
Pill form:Powder form:

3. Organic virgin unprocessed coconut oil (for its monolaurin and lauric acid content): at least 3 tbsp daily to experience health benefits (Fife, 2013).

The only brand I use in our home is this one:

4. Lauricidin: ½ to 1 scoop, one to three times per day


If you have any questions or comments, or if you feel it is necessary to correct something that you read here, feel free to do so below. I appreciate any and all of your contributions. If you think this post could help a friend, share it. You just might change their life.

Legal Disclaimer: The information, including but not limited to, text, graphics, images, website links and other material contained on this website are for informational purposes only. The purpose of this website is to promote broad consumer understanding and knowledge of various health topics, as well as share personal opinions and experiences. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

References

Aravinda, K., Arora, N., Dixit, A., Jatti, D., Kumar, T., & Puri, G. (2018). Efficacy of ozonized olive oil in the management of oral lesions and conditions: A clinical trial. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792056/

Behforooz, A., Griffith, R., Myrmel, K., Thompson, R., & Walsh, D. (1987). Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/3115841

Chaitow, L. (1985). Amino Acids in Therapy: A guide to the therapeutic application of protein constituents. Rochester, VT: Thorsons Publishers Limited.

Fife, B. (2013). The coconut oil miracle. New York, NY: Avery.

Gao, L., Huang, J., Lu, J., Pan, Y., & Xiang, Y. (2018). Topical ozone therapy: An innovative solution to patients with herpes zoster. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/29559601

Lucas, K. & Tomblin, F. (2001). Lysine for management of herpes labialis. Retrieved from https://www.medscape.com/viewarticle/406943_5

Weston A. Price Foundation. (2019). Herpes. Retrieved from https://www.westonaprice.org/health-topics/ask-the-doctor/herpes/

Natural Treatments for Eczema: Amino Acids

Eczema (also known as atopic dermatitis) is a very common autoimmune disorder (presenting on the skin) that affects more than 3 million people per year and is often seen in children and adolescents  Most treatments are topical and are only palliative–they treat the symptoms, not the cause. The skin our largest organ, and whatever presents on the skin is usually due to a systemic problem. People with eczema are experiencing an immune response to systemic inflammation, which can be caused by diet and some individual specific triggers.  As always, I recommend a paleo diet; the elimination of all wheat, grains, processed foods and sugars; and the addition of anti-inflammatory foods and/or supplements as the most important interventions to ameliorate systemic inflammation. Repairing the gut microbiome is essential, and can be done with proper diet and the addition of a quality probiotic.  

Here, we will discuss a recent discovery in genetics and how it relates to eczema, followed by how studies demonstrate that amino acid supplementation can treat and prevent eczema.  

Does eczema run in your family?

It is well known that eczema is more common in people who have a family history of the condition–but why?  Finally, we have some answers. For some patients, there could be a genetic explanation. A team of scientists studied a group of people with severe eczema/atopic dermatitis, and discovered that mutations of a gene called CARD11 appear to be involved its development (National Institutes of Health [NIH], 2017).  They then confirmed that family members of the participants also had the mutations, and also had eczema.  

What does a CARD11 do?

CARD11 gives instructions to a protein (also called CARD11) that stimulates cells of the immune system called T cells by activating the protein complexes NF-κB and mTORC1.  You don’t need to fully understand NF-κB and mTORC1 for our purposes.  You don’t even need to know what the the acronyms mean.  Here is what you do need to know:

Mutations in the CARD11 gene interfere with the proper activation of NF-κB and mTORC1.  In particular, mTORC1 helps transport the essential amino acid L-glutamine into cells, and plays a major role in the normal building of proteins.  Another amino acid that promotes normal mTORC1 functioning is L-Leucine.  

NF-κB plays a role in determining a cells response to stimuli such as stress, free radicals, toxins, oxidation, bacteria or viruses.  It is well understood that abnormal regulation of NF-κB (remember: CARD11 mutations clearly cause this abnormal regulation) leads to autoimmune diseases (like eczema) and other immune system malfunctions.  

Do you have a CARD11 mutation?

Well, if other people in your family have eczema, it is probably safe to assume that you do.  At the very least, you can assume that there is most likely some genetic explanation. If you are reading this and are feeling worried about it being in your genes, it is important to realize that something being “in your genes” does not mean there is nothing you can do about it.  I am a firm believer in the saying: “Genetics load the gun, but environment pulls the trigger.”  

You can change your fate by providing your body with what it needs to overcome this genetic defect.  The findings of the CARD11 study suggest that:

“Supplements of the amino acids glutamine and leucine might help reverse the defects caused by these mutations.” National Institutes of Health, 2017

Interestingly, the evidence that supports the efficacy of amino acid supplementation for eczema is not dependant on whether or not you have a CARD11 mutation.  It appears that specific amino acids help eczema sufferers anyway.  So, if you are the only person in your family with eczema, don’t worry.  These same amino acids can help you just the same! It seems that regardless of the presence of genetic mutation, the same amino acids support the systems that are failing all eczema sufferers.  Which brings me to our discussion of those amino acids…

L-Glutamine:

L-glutamine is a conditionally essential amino acid.  In addition to the study we have already discussed, many other studies demonstrate L-glutamine is effective for eczema.  One study discusses the role of cytoplasmic phospholipase (an enzyme responsible for signaling an inflammatory response) in atopic dermatitis, and how L-glutamine can inhibit that enzyme (Cho et al., 2012).  Inhibition of cytoplasmic phospholipase via L-glutamine supplementation seems to suppress inflammation, itching, and dermatitis (Cho et al., 2012). Although the inflammatory response in this study was induced artificially, the actions of L-glutamine were impressive.  L-glutamine also plays a significant role in maintaining the skin barrier by generating natural moisturizing factors and combining with other amino acids to protect the skin against staph infections (Aoki et al., 2016). Other amino acids that play a role in maintaining the skin barrier include L-histidine and L-arginine (Aoki et al., 2016).    

L-Leucine:

“Leucine is an important component in the process of tissue regeneration and development. Therefore, it can aid improvement of skin lesions and modification of skin barrier function.” – Choopani et al., 2017, Journal of Evidence Based Complementary and Alternative Medicine

In addition, some animal studies have demonstrated that L-leucine supplementation improves skin elasticity, moisture, and wound healing (Hwang et al, 2017; Chinkes et al., 2004).

L-Histidine:

L-histidine is an essential amino acid, which means we must obtain this amino acid from food.  A study conducted by Brown et al. (2017) demonstrated that L-histidine could be a “safe, convenient, nonsteroidal intervention suitable for long-term use in the management of eczema, particularly in children.”  There is not a lot of additional evidence that supports this specifically, but we do know that L-histidine has anti-inflammatory, antioxidant, and immunomodulatory abilities, and and is required for the production of histamine (National Center for Biotechnology Information, 2018).

One more thing . . .

One important cofactor for these amino acids is Vitamin B6.  Vitamin B-6 is a water-soluble vitamin first discovered as a factor that was able to cure dermatitis in rats (Field & Stover, 2015).  This is likely because B6 is a cofactor necessary for more than 100 enzyme reactions in the body (NIH, 2018). Vitamin B3 is important for L-Leucine as well.  Are all the B vitamins in your multivitamin? If not, you might consider taking a B complex. I like this strawberry flavored one by EZ Melts because it contains methylated folate and B12.

If you have any questions or comments, or if you feel it is necessary to correct something that you read here, feel free to do so below. I appreciate any and all of your contributions. If you think this post could help a friend, share it. You just might change their life.

Legal Disclaimer: The information, including but not limited to, text, graphics, images, website links and other material contained on this website are for informational purposes only. The purpose of this website is to promote broad consumer understanding and knowledge of various health topics, as well as share personal opinions and experiences. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

References

Aoki, V., Orfali, R., Samorano, L., & Zaniboni, M. (2016). Skin barrier in atopic dermatitis: beyond filaggrin. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999106/

Brown, S., Gibbs, N., Griffiths, C., Tan, S., & Weller, R. (2017). Feeding filaggrin: effects of l-histidine supplementation in atopic dermatitis. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634381/

Chinkes, D., Wolfe, R., & Zhang, X. (2004). Leucine supplementation has an anabolic effect on proteins in rabbit skin wound and muscle. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/15570031

Cho, B., Im, S., Jin, Z., Jung, S., Kim, H., Lee, C., Lee, H., & Shin, S. (2012). Glutamine suppresses dinitrophenol fluorobenzene-induced allergic contact dermatitis and itching: inhibition of contact dermatitis by glutamine. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/22727501

Choopani, R., Fekri, A., & Mehrbani, M. (2017). Treatment of Atopic Dermatitis From the Perspective of Traditional Persian Medicine: Presentation of a Novel Therapeutic Approach. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871194/

Field, M. & Stover, P. (2015). Vitamin B6. Retireved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288272/

Hwang, J., Lee, J., Lee, W., Park, J., Shin, H., & Song, S. (2017). Oral Administration of Glycine and Leucine Dipeptides Improves Skin Hydration and Elasticity in UVB-Irradiated Hairless Mice. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590797/

National Center for Biotechnology Information. (2018). Histidine. Retrived from https://pubchem.ncbi.nlm.nih.gov/compound/L-histidine

National Institutes of Health. (2017). Gene mutations suggest potential treatment strategy for severe eczema. Retrieved from https://www.nih.gov/news-events/nih-research-matters/gene-mutations-suggest-potential-treatment-strategy-severe-eczema

National Institutes of Health. (2018). Vitamin B6. Retrieved from https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/